THE HIPPO PATHWAY TERMINAL EFFECTOR TAZ/WWTR1 MEDIATES OXALIPLATIN SENSITIVITY IN P53 PROFICIENT COLON CANCER CELLS

The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells

Abstract YAP and TAZ, the Hippo pathway terminal transcriptional activators, are frequently upregulated in cancers.In tumor cells, they have been mainly associated with increased tumorigenesis controlling different aspects from cell cycle regulation, stemness, or resistance to chemotherapies.In fewer cases, they have also been Fusible Non-Woven sho

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White oak (Quercus fabri Hance) regenerated stump sprouts show few senescence symptoms during 40 years of growth in a natural forest

Abstract Background The relationship between physiological age of parental trees and lifespan of clonal offspring is unclear.White oak (Quercus fabri Hance) has a high sprouting capability after harvest, with the regenerated sprouts being typical clonal individuals.To determine whether regenerated sprouts undergo rapid senescence compared with the

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